Global logistics aim to optimize and control the material/product flow and the information flow so that materials/products can be moved at a desired pace, in a proper fashion and at the right volume. The production processes in the medical equipment manufacturing industries are highly automated and dynamic and the orders are customized. This study presents an intelligent global logistics system for scheduling and planning of medical equipment production systems to minimize logistics cost. The optimization technique for production scheduling in the supply chains of medical equipments shows how an intelligent logistics system can effectively solve real-world problem. This research develops an intelligent decision system for global logistics of medial equipment manufacturing system. The proposed system is verified with real-world application. Medical equipment manufacturers can get benefit of the proposed optimization system.