Volume 29, Number 6, 1114-1116, DOI: 10.1007/s00270-005-0133-x

Aggravation of Pre-Existing Atrioventricular Block, Wenckebach Type, Provoked by Application of X-Ray Contrast Medium

Marianne Brodmann, Gerald Seinost, Gerhard Stark and Ernst Pilger

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Abstract

Background  

Significant bradycardia followed by cardiac arrest related to single bolus administration of X-ray contrast medium into a peripheral artery has not, to our knowledge, been described in the literature.

Methods and Results  

While performing a percutaneous transluminal angioplasty of the left superficial femoral artery in a 68-year old patient with a pre-existing atrioventricular (AV) block, Wenckebach type, he developed an AV block III after a single bolus injection of intra-arterial X-ray contrast medium.

Conclusion  

We believe that application of contrast medium causes a transitory ischemia in the obstructed vessel and therefore elevation of endogenous adenosine. In the case of a previously damaged AV node this elevation of endogenous adenosine may be responsible for the development of a short period of third-degree AV block.

Keywords  Adenosine - Atrioventricular node - Contrast medium - Percutaneous transluminal angioplasty

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