Foot ulceration with infection is one of the leading causes of hospitalization for patients with diabetes mellitus. Although solid data on the true incidence and prevalence of diabetic foot ulcerations do not exist, it is believed that approx 15% of patients with diabetes will develop a foot or leg ulceration in their lifetime (1). The rate of recidivism is also staggering in this population with 50% of ulcerations recurring within 18 months. The number of lower extremity amputations among patients with diabetes has been well documented for years. Patients with diabetes are 15 times more likely to undergo a major lower extremity amputation than patients without diabetes, with the total number of major limb amputations being more than 50,000 (2).