Long-term results for 167 cases of the fat injection technique performed between June 1983 and June 1987 are presented. During this four-year period, stable results appear to have been obtained in only a few cases. This report also includes the disappointing preliminary findings of attempts to use fat to fill wrinkles in the face. Although these preliminary long-term results may not be encouraging, various laboratory studies seem to demonstrate the hypothetical possibility of fat cell survival and tend to encourage continued research in this field.