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The most common conjunctival tumor is the nevus |
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Conjunctival nevi can be pigmented or non-pigmented and often display cysts |
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Conjunctival melanoma is rare but is slightly more common nowadays, similar to cutaneous melanoma |
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Conjunctival melanoma can arise from a conjunctival nevus, conjunctival primary acquired melanosis, or de novo |
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In the USA, squamous cell carcinoma most often occurs in elderly Caucasian males |
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Topical chemotherapy is most useful for conjunctival squamous cell carcinoma or intraepithelial neoplasia and it is less effective
for primary acquired melanosis. Topical chemotherapy is not effective for conjunctival melanoma
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Amelanotic melanoma and pagetoid invasion of eyelid sebaceous carcinoma can simulate conjunctival squamous cell carcinoma
and differentiation histopathologically is important
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Lymphoid tumors tend to occur in the fornix of the conjunctiva and, if bilateral, strongly suggest the presence of systemic
lymphoma
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