The antignawing activity of the steam distillate of
Thujopsis dolabrata S. et. Z. var.
hondai sawdust against mice was evaluated using a wire-dipping method. This method is suitable for measuring repellent activities of chemicals and plant-derived materials. The steam distillate of the
Thujopsis sawdust was shown to have potent antignawing activity. Three terpenoid compounds with antignawing activity were isolated from the steam distillate of the
Thujopsis sawdust: thujopsene, carvacrol, and

-thujaplicine. Carvacrol exhibited the most potent repellent activity. As a naturally occurring repellent, carvacrol could be useful as new preventive agent against various kinds of damage caused by rodents.
Key Words Rodent - mouse - repellent - antignawing activity - wire-dipping method -
Thujopsis dolabrata S. et. Z. var.hondai
- carvacrol - terpenoid