Volume 21, Number 3, 263-271, DOI: 10.1007/BF02036716

Antignawing factor of crude oil derived fromThujopsis dolabrata S. et Z. var.hondai sawdust against mice

Young-Joon Ahn, Sung-Baek Lee, Tsutomu Okubo and Mujo Kim

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Abstract

The antignawing activity of the steam distillate ofThujopsis dolabrata S. et. Z. var.hondai sawdust against mice was evaluated using a wire-dipping method. This method is suitable for measuring repellent activities of chemicals and plant-derived materials. The steam distillate of theThujopsis sawdust was shown to have potent antignawing activity. Three terpenoid compounds with antignawing activity were isolated from the steam distillate of theThujopsis sawdust: thujopsene, carvacrol, andbeta-thujaplicine. Carvacrol exhibited the most potent repellent activity. As a naturally occurring repellent, carvacrol could be useful as new preventive agent against various kinds of damage caused by rodents.

Key Words  Rodent - mouse - repellent - antignawing activity - wire-dipping method -  Thujopsis dolabrata S. et. Z. var.hondai  - carvacrol - terpenoid

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