Polyclonal Activation as a Consequence of Infection of Mice with Yersinia enterocolitica O:3 Isolated from Patients with or without Arthritis

Beatriz Medeiros, Eloisa Silva, Orivaldo Ramos and Deise Falcão

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Abstract

It was observed polyclonal activation of B-lymphocytes with all the bacterial strains tested. The IgG2a and IgG3 isotypes were that which present the major activation. The three bacterial strains stimulated the production of autoantibodies against all the autologous constituents tested.

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Polyclonal Activation as a Consequence of Infection of Mice with Yersinia enterocolitica O:3 Isolated from Patients with or without Arthritis

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Abstract

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