NIH Category III chronic prostatitis/chronic pelvic pain syndrome is associated with neuromuscular abnormalities as manifested by pain, voiding, and sexual dysfunction. With techniques adopted from physical therapy, these abnormalities can be more readily identified and treated. Techniques such as biofeedback, myofascial trigger point release, and relaxation have been applied successfully in this group of patients. This approach, although more time consuming and low tech, affords patients with safe effective tools for self care and empowerment.