The Einstein field equations for an irrotational perfect fluid with pressurep, equal to energy density are studied when the space-time is conformally flat. The coordinate transformation to co-moving coordinates is discussed. The energy and Hawking-Penrose inequalities are studied. Static and non-static solutions of the field equations are obtained. It is interesting to note that in the static case the only spherically-symmetric conformally flat solution for self-gravitating fluid is simply the empty flat space-time of general relativity.