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Review Article

Can we improve outcome of congenital diaphragmatic hernia?

L. van den Hout1, I. Sluiter1, S. Gischler1, A. De Klein2, R. Rottier1, H. Ijsselstijn1, I. Reiss1 and D. Tibboel1, 3 Contact Information

(1)  Department of Paediatric Surgery, ErasmusMC-Sophia, Rotterdam, The Netherlands
(2)  Department of Genetics, ErasmusMC-Sophia, Rotterdam, The Netherlands
(3)  ErasmusMC-Sophia, Room SK-3284, P.O. Box 2060, 3000CB Rotterdam, The Netherlands

Published online: 9 August 2009

Abstract  This review gives an overview of the disease spectrum of congenital diaphragmatic hernia (CDH). Etiological factors, prenatal predictors of survival, new treatment strategies and long-term morbidity are described. Early recognition of problems and improvement of treatment strategies in CDH patients may increase survival and prevent secondary morbidity. Multidisciplinary healthcare is necessary to improve healthcare for CDH patients. Absence of international therapy guidelines, lack of evidence of many therapeutic modalities and the relative low number of CDH patients calls for cooperation between centers with an expertise in the treatment of CDH patients. The international CDH Euro-Consortium is an example of such a collaborative network, which enhances exchange of knowledge, future research and development of treatment protocols.

Keywords  Congenital diaphragmatic hernia - Treatment strategies - Follow-up - CDH Euro-Consortium

On behalf of the CDH Euro-Consortium.
D. Tibboel presented the work at the 21st congress of the Asian Association of Pediatric Surgeons, Bangkok, Thailand, 16–19 November 2008.

Contact Information D. Tibboel
Email: d.tibboel@erasmusmc.nl

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