Obesity is an increasingly prevalent condition in our society. The majority of hysterectomies are still being undertaken abdominally. Obese patients have a high rate of complications from abdominal surgery. Laparo-vaginal hysterectomy has a faster recovery than abdominal hysterectomy. If the uterine vessels are ligated laparoscopically at laparo-vaginal hysterectomy, there is a low conversion rate to abdominal hysterectomy. The aim of this study was to establish whether laparoscopic hysterectomy is a feasible alternative in obese patients. A 7-year audit of patients requiring a hysterectomy identified 27 women weighing 100 kg or more. All patients gave informed consent to an initial laparoscopic procedure, having been assessed as suitable for such, and then had a laparoscopic hysterectomy performed. Data regarding their operation was prospectively collected and retrospectively reviewed. All patients had successful laparoscopic hysterectomies with none requiring conversion to open operation, reoperation or readmission. There were no major complications. The postoperative stay was short (mean 2.4 days), but operation times were long (mean 175 min). Laparoscopic hysterectomy is a feasible alternative to abdominal hysterectomy in obese patients weighing 100 kg or more with low morbidity and fast recovery with short hospital stay.