There is great variability among AD patients, and within the same patient over time. AD is not yet well enough understood for universally effective treatments to be available. The case-based reasoning (CBR) research paradigm complements the medical research approach of finding treatments effective for all patients by matching patients to treatments that were effective for similar patients in the past.

The Auguste Project is an effort to provide decision support for planning the ongoing care of AD patients, using CBR and other thought processes natural to members of geriatric interdisciplinary teams. System prototypes are used to explore the reasoning processes involved and to provide the forerunners of practical clinical tools. The first system prototype has just been completed. This prototype supports the decision to prescribe neuroleptic drugs to AD patients with behavioral problems. It uses CBR to determine if a neuroleptic drug should be prescribed and rule-based reasoning to select one of five approved neuroleptic drugs for a patient. The first system prototype serves as proof of concept that CBR is useful for planning ongoing care for AD patients. Additional prototypes are planned to explore the research issues raised.