BACKGROUND
Prognostic information is becoming increasingly important for clinical decision-making.
OBJECTIVE
To develop and validate an index to predict 5-year mortality among community-dwelling older adults.
DESIGN AND PARTICIPANTS
A total of 24,115 individuals aged >65 who responded to the 1997-2000 National Health Interview Survey (NHIS) with follow-up
through 31 December 2002 from the National Death Index; 16,077 were randomly selected for the development cohort and 8,038
for the validation cohort.
MEASUREMENTS
39 risk factors (functional measures, illnesses, behaviors, demographics) were included in a multivariable Cox proportional
hazards model to determine factors independently associated with mortality. Risk scores were calculated for participants using
points derived from the final model’s beta coefficients. To evaluate external validity, we compared survival by quintile of
risk between the development and validation cohorts.
RESULTS
Seventeen percent of participants had died by the end of the study. The final model included 11 variables: age (1 point for
70-74 up to 7 points for >85); male: 3 points; BMI <25: 2 points; perceived health (good: 1 point, fair/poor: 2 points); emphysema:
2 points; cancer: 2 points; diabetes: 2 points; dependent in instrumental activities of daily living: 2 points; difficulty
walking: 3 points; smoker-former: 1 point, smoker-current: 3 points; past year hospitalizations-one: 1 point, >2: 3 points.
We observed close agreement between 5-year mortality in the two cohorts; which ranged from 5% in the lowest risk quintile
to 50% in the highest risk quintile in the validation cohort.
CONCLUSIONS
This validated mortality index can be used to account for participant life expectancy in analyses using NHIS data.
KEY WORDS mortality prediction - life expectancy - prevention - older adults
This abstract was presented in part at the 2009 meeting of the American Geriatrics Society, Chicago, IL.